Launched in 2017 by microbiome research leader BIFIDO (Korea’s top probiotic manufacturer), Ma:nyo specializes in fermented skincare using live bifida ferment lysate (4.2 billion CFU/g) stabilized through patented lyophilization technology. Their Biome Balance Complex, developed with Seoul National University, reconstructs skin microbiota diversity by 67% after 28 days of use. The brand introduced the world’s first “Microbiome QR Code” tracking system, allowing customers to verify the viability of probiotics in their products. Ma:nyo’s factory maintains ISO Class 7 cleanroom standards typically reserved for vaccine production.